GABA(A) receptors are ligand-gated ion stations comprising five subunits from 8 subfamilies, each assembled in four hydrophobic transmembrane domains. 64 HEK-293T cells122 66.5 6.8 6.62 2.11[62] 73 oocytes122S 84.5 4.930 [54] 74 oocytes122S 38.4 4.830 [54] 84 oocytes122L40/20 M90.6/9710014.7/8.7[56] 96 oocytes122L40/5 M51/4010029.2/11.7[56] 134 oocytes122L 5.79[108] 154 Dorsal root ganglia 300 M1003021[117] 154 HEK-293T cells12 60300 [118] 197 oocytes122L300 M 11.9 1.7[152] 210 oocytes122L300 M 10.1 2.9[152] 210 oocytes122L300 M 12.0 2.2[152] 212 oocytes122SEC5C10302 2630052 9[25] 6 oocytes122SEC5C10187 1030056 19[25] 20 oocytes1221 M295 50300 [33] 31C33 oocytes122 110C440 0.6C3.5[40] 46 oocytes122EC157 6303[48] 66 Xenopus oocytes122EC2C547 510 [57] 82 oocytes44 68 5100 [76] 88 oocytes122SEC3C10578.5 68.8 8.1 1.4[79] 89 oocytes122SEC3C10267.6 56.6 5.0 2.3[79] 90 oocytes122SEC3C10604.9 108.2 15.0 3.6[79] 92 oocytes122S 730.4 76.710013.8 1.5[81] 93 oocytes122S 715.8 56.110016.7 2.0[81] 94 oocytes122S 719.3 63.310013.4 1.6[81] 95 oocytes122SEC5C10552.73 84.075002.8 1.4[82] 97 oocytes122SEC3C10891.5 163.0 4.0 2.4[79] 101 HEK-293T cells122 290 28[86] 102 oocytes122SEC5C101200 163500171.5 34.6[87] 103 oocytes122S 1315 28130036.2 14.7[88] 106 HEK-293T cells 10.1 10.5[93] 107 HEK-293T cells 16.9 0.3[93] 108 HEK-293T cells 10.5 2.3[93] 109 Cortical neurons 10 M158 2010.04258[94] 110 oocytes122SEC5C10218.1 20.8 21.8 7.5[96] 112 oocytes122SEC5C10245.0 59.6 52.2 24.8[96] 113 oocytes122SEC5C10885.8 291.2 135.6 85.7[96] 114 oocytes122SEC5C10168.7 41.5 36.6 16.4[96] 115 oocytes122SEC5C10129.7 36.8 118.7 54.4[96] 116 oocytes122SEC5C10395.6 27.2 31.5 7.1[96] 117 oocytes122SEC5C10288.8 23.7 12.8 3.1[96] 118 oocytes122SEC5C10793.4 107.4 79.2 19.4[96] 119 oocytes122SEC5C10362.5 87.1 54.6 28.8[96] 121 oocytes122S 54 13[99] 121 oocytes122SEC5C1025.8 12.7300 [100] 122 oocytes122S 57 4[99] 124 oocytes122S 550 7110025 8[99] 125 oocytes122S 34 6[99] 126 oocytes122SEC5C10204.5 33.2300 [89] 127 oocytes122S 124 1110014 1[99] 127 oocytes122SEC5C10273.6 39.4300 [100] 128 oocytes122SEC5C1061.2 20.2300 [100] 129 oocytes122SEC5C1038.0 21.3300 [100] 131 oocytes122S 144.6 35.3500140.2 51.2[106] 132 oocytes122LEC10 (3 M)126 1510058.24[108] 135 oocytes122SEC3C10786.8 72.1300175.5 25.5[109] 136 oocytes122SEC3C101512.9 176.530052.5 17.0[109] 137 oocytes122SEC5C10771.09 57.9450040.7 4.08[82] 138 oocytes122SEC5C10640.02 53.565008.6 1.6[82] 139 oocytes122SEC5C10490.97 22.3450018.8 2.3[82] 140 oocytes122SEC5C10188 2030031 8[110] 141 oocytes122SEC5C10239 Actinomycin D supplier 1830027 6[110] 149 oocytes122LEC5C141251 F2RL2 73300247.7[115] 150 oocytes122LEC15C241106 73300236.9[115] 151 oocytes122LEC25C39571 123300111.2[115] 152 Actinomycin D supplier oocytes122LEC15C24968 88300190.5[115] 153 oocytes122LEC15C24377 156300469.1[115] 160 oocytes132SEC20416 72100 [123] 161 oocytes1221 M224 85300 [33] 162 oocytes1221 M453 176300 [33] 163 oocytes1221 M340 70300 Actinomycin D supplier [33] 164 oocytes1221 Actinomycin D supplier M213 105300 [33] 165 oocytes1221 M477 68300 [33] 166 oocytes1221 M809 118300 [33] 167 HEK-293T cells1221 M156 261000 [33] 168 HEK-293T cells1221 M168 421000 [33] 169 HEK-293T cells1221 M116 561000 [33] 170 HEK-293T cells1221 M179 551000 [33] 171 oocytes1221 M737 234300 [33] 175 Xenopus oocytes122SEC20496 113100 [131] 175 Xenopus oocytes122SEC2096.2 3.850 [132] 176 oocytes122SEC5C10834.6 77.5 70.6 12.2[96] 177 HEK-293T cells1221 M117 571000 [33] 178 HEK-293T cells1221 M115 521000 [33] 179 Rhizoma curcumae oilHEK-293T cells1221 M133 1050 [107] 180 Rhizoma curcumae oilHEK-293T cells1221 M251 1630034.4 2.9[107] 182 oocytes122SEC5C10400.0 77.610013.6 4.1[135] 183 oocytes122SEC5C10383.5 89.3 57.3 19.7[96] 184 oocytes122SEC5C10413.4 66.3 118.4 29.9[96] 188 oocytes122SEC5C10241 23.150034.0 6.7[87] 189 oocytes122SEC5C10669 112100064.8 19.8[87] 190 oocytes122SEC5C10164 42.9500109.4 46.6[87] 191 oocytes122SEC5C10886 1051000135.1 34.4[87] 192 oocytes122SEC5C10588 12630065.3 21.6[87] 193 oocytes122SEC5C1070.7 2.6100056.02 5.09[140] 194 oocytes122SEC1C1096 330012 1[141] 195 oocytes122SEC1C10166 12230070 17[141] 196 oocytes122SEC1C10157 1230099 20[141] 198 oocytes112SEC2018010.05 0.02[145] 202 oocytes122SEC5C10397.5 34.01008.7 1.3[148] 203 oocytes122SEC5C10425.2 96.5500141.6 68.0[149] 204 oocytes122SEC5C10855.7 114.950033.2 8.7[149] 207 oocytes122SEC3C10309.4 35.630024.9 8.8[151] 208 oocytes122SEC3C10211.0 26.030035.7 8.8[151] 220 oocytes122S10 M 53.2 12.3[162] 221 oocytes122S10 M23.3 1.410023.1 8.6[163] 222 oocytes122S10 M54.1 1.710017.1 2.2[163] 228 oocytes122SEC3C10378 6430036 14[167] 229 oocytes122SEC3C10256 4030028 17[167] 230 oocytes122SEC3C10289 4530026 7[167] 231 oocytes122SEC3C101947 18530027 8[167] Open in a separate window Table 3 Data from radioligand binding.