Supplementary MaterialsData. performed to functionally characterize the fusion. Results Expression of the KLK2-FGFR2 fusion proteins in NIH3T3 cells induced a deep morphological change marketing improved migration and activation of downstream protein in FGFR signaling pathways. The KLK2-FGFR2 fusion proteins was motivated to become delicate towards the selective FGFR inhibitors AZD-4547 extremely, BGJ398, JNJ-42756943, the irreversible… Continue reading Supplementary MaterialsData