It is still a controversy whether the part of Sirtuin 7 (SIRT7) is an oncogene or a tumor suppressor gene in malignancy while SIRT7 may have different functions in different types of malignancy. IL12RB2 silencing of CDC4 partially rescued SIRT7 knockdown-mediated inhibitory effects on expansion, migration, and attack of osteosarcoma cells. In summary, our results… Continue reading It is still a controversy whether the part of Sirtuin 7