Supplementary MaterialsSupplementary Data. length is usually telomerase dependent without TMP 269 impacting telomerase biogenesis or targeting of the enzyme to telomeres. Instead, RTEL1 depletion led to a decrease in both G-overhang content TMP 269 and POT1 association with telomeres with limited telomere uncapping. Strikingly, overexpression of POT1 restored telomere length but not the overhang, demonstrating… Continue reading Supplementary MaterialsSupplementary Data. length is usually telomerase dependent without TMP
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Microglia are increasingly named critical in the pathogenesis of pain hypersensitivity
Microglia are increasingly named critical in the pathogenesis of pain hypersensitivity caused by injury to peripheral nerves. pain arises as a consequence of cells damage/swelling and neuropathic pain from nervous program lesions. As opposed to inflammatory discomfort hypersensitivity which often returns on track if the condition process is normally controlled neuropathic discomfort persists long following… Continue reading Microglia are increasingly named critical in the pathogenesis of pain hypersensitivity