Cyclin-dependent kinase 1 (CDK1) inhibitory phosphorylation controls the onset of mitosis and is vital for the checkpoint pathways that avoid CYFIP1 the G2- to M-phase transition in cells with unreplicated or broken DNA. cyclin E-CDK2 activity once the CDK inhibitor p21 was knocked down also. We were amazed to find that was inadequate to trigger… Continue reading Cyclin-dependent kinase 1 (CDK1) inhibitory phosphorylation controls the onset of mitosis