MK-8776 is a recently described inhibitor that’s highly selective for checkpoint kinase 1 (Chk1), that may weaken the DNA restoration capacity in malignancy cells to accomplish chemo-sensitization. DNA harm by MK-8776, inhibited the cell proliferation and improved the radiosensitivity from the 3 TNBC cell lines. Comparable results were acquired in MDA-MB-231 xenograft tumors in nude… Continue reading MK-8776 is a recently described inhibitor that’s highly selective for checkpoint