Receptor interacting protein 3 (Grab3) is a protein kinase essential for TNF-induced necroptosis. further exposed that the connection of Grab3 with MLKL prevented massive irregular Grab3 aggregation, and consequently should become important for formation of the amyloid signaling compound of necrosomes. We also found that the connection between Grab3 and MLKL is definitely required for… Continue reading Receptor interacting protein 3 (Grab3) is a protein kinase essential for