We devised a model system to study persistent contamination by the tick-borne flavivirus Langat computer virus (LGTV) in 293T cells. 15 passages, DIPs constituted approximately 34% of the total LGTV populace (coverage of 1,293-fold). Furthermore, at this point, one specific DIP populace predominated in which nucleotides 1058 to 2881 had been deleted. This defective genome… Continue reading We devised a model system to study persistent contamination by the