History Collagen XXIII is a transmembrane collagen previously shown to be upregulated in metastatic prostate malignancy. was analyzed in three independent cohorts using TMAs with representative tumor and control lung cells from NSCLC individuals. In addition NSCLC patient urine samples were analyzed for the presence of collagen XXIII via Western Trichostatin-A blot. Results Collagen XXIII… Continue reading History Collagen XXIII is a transmembrane collagen previously shown to be
Tag: CCNB1
The phosphatidylinositol 3-kinase (PI3K) signaling axis impacts on cancer cell growth
The phosphatidylinositol 3-kinase (PI3K) signaling axis impacts on cancer cell growth survival motility and metabolism. its use in therapeutics and increases the need to develop sophisticated strategies for its use. With this review we will discuss how PI3K signaling affects the growth and survival of tumor cells. From this vantage we will consider how inhibitors… Continue reading The phosphatidylinositol 3-kinase (PI3K) signaling axis impacts on cancer cell growth