A reliable imaging method to localize transplanted cells and monitor their viability would enable a systematic investigation of cell therapy. in the urologic field. This review focuses on the current role and limitations of MRI with labeled nanoparticles for tracking transplanted stem cells in urology. 1. Introduction Molecular imaging technologies have developed recently and facilitate… Continue reading A reliable imaging method to localize transplanted cells and monitor their
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Focal adhesion kinase (FAK) controls adhesion-dependent cell motility survival and proliferation.
Focal adhesion kinase (FAK) controls adhesion-dependent cell motility survival and proliferation. motif on FERM that regulates co-activation and nuclear localization. FAK dimerization requires local enrichment which occurs specifically at focal adhesions. Paxillin plays a dual role by recruiting FAK to focal adhesions and by reinforcing the FAT:FERM interaction. Our results provide a structural and mechanistic… Continue reading Focal adhesion kinase (FAK) controls adhesion-dependent cell motility survival and proliferation.