The mechanisms that safeguard cells against chromosomal instability (CIN) are of great interest, as CIN contributes to tumorigenesis. amount of systems for mending DNA harm, double-strand fractures (DSBs) are especially frustrating (Su, 2006). Failing to fix DSBs outcomes in chromosome fragments lacking either centromeres or telomeres. It is normally well set up that without the… Continue reading The mechanisms that safeguard cells against chromosomal instability (CIN) are of