RecQ DNA helicases are critical enzymes for the maintenance of genome integrity. activity or nucleotide occupancy to ssDNA binding. The interaction of the ARL with the DNA is also observed in LY 344864 structures of DNA complexes of both RecQ [PDB ID code 4TMU (21)] and human BLM (PDB ID code 4CGZ). A structure-based sequence… Continue reading RecQ DNA helicases are critical enzymes for the maintenance of genome