Introduction First/Second-hand cigarette-smoke (FHS/SHS) exposure weakens immune defenses inducing chronic obstructive pulmonary disease (COPD) but the underlying mechanisms are not fully understood. matrix proteins that form a biofilm involved in pathogenesis of chronic lung disease [13 27 30 31 32 Furthermore these chronic bacterial exacerbations are the major cause of mortality in CF/COPD subjects [22… Continue reading Introduction First/Second-hand cigarette-smoke (FHS/SHS) exposure weakens immune defenses inducing chronic obstructive