Disruption of the complete balance of negative and positive molecular regulators of bloodstream and lymphatic vessels can result in myriad illnesses that affect one particular in 4 people worldwide. Pathological replies of the parallel circulatory systems can result in diseases as mixed as age-related macular degeneration, atherosclerosis, cancers, lymphedema, arthritis rheumatoid, and tumor metastasis1. Collectively,… Continue reading Disruption of the complete balance of negative and positive molecular regulators
Tag: CUDC-907
Objective Scleroderma patients with autoantibodies to centromere proteins (CENPs) and/or interferon-inducible
Objective Scleroderma patients with autoantibodies to centromere proteins (CENPs) and/or interferon-inducible protein 16 (IFI16) are at increased risk of severe vascular complications. cells in biopsies from scleroderma patients and CUDC-907 normal controls. Flow cytometry analysis revealed IFI16 expression in CPCs, but minimal expression in CECs. Conclusion Expression of scleroderma autoantigens IFI16 and CENPs, which are… Continue reading Objective Scleroderma patients with autoantibodies to centromere proteins (CENPs) and/or interferon-inducible