This perspective on Deng et al. elements within the tumor microenvironment (1-3). Although myriad genetic and epigenetic alterations in tumor suppressors and oncogenes underlie autonomous defects of malignancy cells host cells play additional key functions in modulating oncogenic pathways. Secreted and membrane-bound factors produced in the stroma may stimulate tumor-cell growth and survival during early… Continue reading This perspective on Deng et al. elements within the tumor microenvironment