To investigate the quantitative response of energy metabolic pathways in human MCF-7 breast malignancy cells to hypoxia glucose deprivation and estradiol stimulation we developed a targeted proteomics assay for accurate quantification of protein expression in glycolysis/gluconeogenesis TCA cycle and pentose phosphate pathways. pathway enzymes (FBP1 IDH2 and G6PD) that are known to redirect cellular metabolism… Continue reading To investigate the quantitative response of energy metabolic pathways in human