History. assays. This EGFR influence on FOXC1 manifestation was verified using the MDA-MB-468 xenograft model. Outcomes. Both FOXC1 mRNA and proteins levels considerably correlated with EGFR appearance in human breasts tumors. EGFR activation induced FOXC1 transcription through the ERK and Akt pathways in BLBC. EGFR inhibition in vivo decreased FOXC1 appearance in xenograft tumors. We… Continue reading History. assays. This EGFR influence on FOXC1 manifestation was verified using