The constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are important nuclear receptors mixed up in regulation of cellular responses from contact with many xenobiotics and different physiological processes. to CAR activation elevated cell proliferation development of changed hepatic foci and GF 109203X eventually the introduction of liver organ tumors. Associative occasions in the… Continue reading The constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are
Tag: GF 109203X
Background Neuroblastoma (NB) is the most common extracranial solid tumor in
Background Neuroblastoma (NB) is the most common extracranial solid tumor in children. Changes in tumorigenicity were assayed by soft agar colony forming ability. N-myc binding to miR-375 promoter was assayed by chromatin-immunoprecipitation. Results Unsupervised hierarchical clustering of miRNA microarray data segregated neuroblastic and non-neuronal cell lines and showed that specific miRNAs define each phenotype. qRT-PCR… Continue reading Background Neuroblastoma (NB) is the most common extracranial solid tumor in