SIRT1 is really a NAD+-dependent deacetylase considered to regulate cellular metabolic pathways in response to modifications in nutrient flux. blood sugar was infused and hyperglycaemia was maintained in ~11mM afterwards. After 5 hours 11 blood sugar induced significant insulin level of resistance in skeletal muscles. Oddly enough overexpression of either SIRT1 or SIRT1 (H363Y) for… Continue reading SIRT1 is really a NAD+-dependent deacetylase considered to regulate cellular metabolic