Brain put through acute ischemic attack caused by an arterial blockage needs immediate arterial recanalization. that reperfusion after forebrain ischemia dramatically increases phosphorylation level of extracellular signal-regulated kinase 2 (ERK2) in the gerbil hippocampus. In addition i.v. administration of U0126 (100-200 mg/kg) a specific inhibitor of MEK (MAPK/ERK kinase) protects the hippocampus against forebrain ischemia.… Continue reading Brain put through acute ischemic attack caused by an arterial blockage