The epidermal growth factor receptor (EGFR) is overexpressed in many cancers, including breast, ovarian, endometrial and non-small cell lung cancer. C, 2 h, 71%. Tr-MAG3 (12) was synthesized by the same procedure as 11, except using triglycine instead of glycine. Tr-MAG (11) was conjugated with compound 8 with DCC as condensation agent and 4-dimethylaminopyridine (DMAP)… Continue reading The epidermal growth factor receptor (EGFR) is overexpressed in many cancers,