The specific localization of L-type Ca2+ channels in skeletal muscle triads is critical for his or her normal function in excitation-contraction (EC) coupling. Whereas chimeras filled with the COOH terminus of α1A weren’t included into triads chimeras filled with the COOH terminus of α1S had PD0325901 been properly targeted. Mapping from the COOH terminus uncovered… Continue reading The specific localization of L-type Ca2+ channels in skeletal muscle triads