Parkinson’s disease (PD) is characterized by selective reduction of dopaminergic neurons in the pars compacta of the substantia nigra and deposition of ubiquitinated protein in aggregates called Lewy systems. accumulates on the external membrane layer of broken mitochondria selectively, which outcomes in phosphorylation and recruitment of parkin JNJ-38877605 and ubiquitin. White1-turned on parkin and phosphorylated… Continue reading Parkinson’s disease (PD) is characterized by selective reduction of dopaminergic neurons