Proteins lysine acetyltransferases (HATs or PATs) acetylate histones and other proteins and are principally modeled as transcriptional coactivators. Analysis of CBP and p300 mutant mouse fibroblasts reveals CBP/p300 are together chiefly responsible for the global acetylation of histone H3 residues K18 and K27 and contribute to other locus-specific histone acetylation events. CBP/p300 can also be… Continue reading Proteins lysine acetyltransferases (HATs or PATs) acetylate histones and other proteins