Supplementary MaterialsFigure S1 41419_2019_1919_MOESM1_ESM. in the mouse model. Finally, we demonstrated that p53 manifestation could be governed with the ATF6/XBP1/CHOP axis to market the introduction of CP. We as a result conclude that ATF6 signalling regulates CP development by modulating pancreatic acinar cell apoptosis, which gives a target for ER stress-based treatment and diagnosis of… Continue reading Supplementary MaterialsFigure S1 41419_2019_1919_MOESM1_ESM. in the mouse model. Finally, we demonstrated