Anti-angiogenic agents such as for example bevacizumab (BEV) can induce normalization of the blood brain barrier which may PF-06687859 influence PF-06687859 the penetration and activity of a co-administered cytotoxic drug. U87 human glioma. Ten or eleven days after tumor inoculation animals bearing U251 and U87 respectively were treated with: TMZ alone (50 mg/kg for 5… Continue reading Anti-angiogenic agents such as for example bevacizumab (BEV) can induce normalization