Supplementary Materialsmolecules-23-03114-s001. Leu377, and Lys458 had been key amino acidity residues for Syk inhibitory activity. This research showed that tanshinone I is normally a Syk inhibitor with mast cell degranulation inhibitory activity. Tanshinone I may be a potential lead compound for developing effective and safe Syk-inhibiting medicines. 0.05) (Figure 3). A further dose-effect analysis found… Continue reading Supplementary Materialsmolecules-23-03114-s001. Leu377, and Lys458 had been key amino acidity residues