We established a differentiation method for homogeneous α7 integrin-positive human skeletal muscle mass stem cell (α7+hSMSC)-derived osteoblast-like (α7+hSMSC-OB) cells and found that interleukin (IL)-1β induces matrix metalloproteinase (MMP)-13-regulated proliferation of these cells. the proliferation rate of these cells. Treatment with small interfering RNAs against Wnt16 and Lrp5 suppressed the IL-1β-induced increase in cell proliferation. We… Continue reading We established a differentiation method for homogeneous α7 integrin-positive human skeletal