Purpose Elevated ZAP-70 expression predicts poor prognosis in chronic lymphocytic leukemia (CLL). methylated in normal B cells. Large correlation with mRNA and protein expression as well as activity in promoter reporter assays exposed that within this differentially methylated region a single CpG dinucleotide and neighboring nucleotides are particularly important in transcriptional rules. Furthermore by using… Continue reading Purpose Elevated ZAP-70 expression predicts poor prognosis in chronic lymphocytic leukemia