Mutations in the heart and muscle mass isoform of adenine nucleotide translocator 1 (ANT1) are associated with autosomal-dominant progressive external opthalmoplegia (adPEO) clinically characterized by exercise intolerance, ptosis and muscle weakness. properties of mutant ANT1 can be responsible for disease pathogenesis in order Bosutinib adPEO, because exchange reversal happening at higher than normal order Bosutinib… Continue reading Mutations in the heart and muscle mass isoform of adenine nucleotide