Supplementary MaterialsNIHMS835629-supplement-supplement_1. hypothesized that IL10R1 expression on IEC is usually regulated by Trp metabolites. Analysis of the promoter region of IL10R1 revealed a functional aryl hydrocarbon response element (AHRE), which is usually induced by Kyn in luciferase-based IL10R1 promoter assays. Additionally, this analysis confirmed that IL10R1 protein levels were increased in response to Kyn in… Continue reading Supplementary MaterialsNIHMS835629-supplement-supplement_1. hypothesized that IL10R1 expression on IEC is usually regulated