Supplementary MaterialsESM 1: (DOCX 407?kb) 424_2014_1608_MOESM1_ESM. control tissue, whereas that of NHE3 or NHERF1 was not. Inflamed individual and murine intestinal tissue displayed correct clean boundary localization of NHE3 but decreased acid-activated NHE3 transportation activity. An identical NHE3 transportation defect was noticed when PDZK1 proteins content was reduced by shRNA knockdown in Caco-2BBe cells or… Continue reading Supplementary MaterialsESM 1: (DOCX 407?kb) 424_2014_1608_MOESM1_ESM. control tissue, whereas that of