Interstrand crosslinks induce DNA duplication fork holding on that in convert

Interstrand crosslinks induce DNA duplication fork holding on that in convert activates the ATR-dependent gate and DNA fix on nuclear chromatin. of gadd45 mRNA. Significantly, bumping down g53 via shRNA do not really slow down the DMC-induced disassociation of ATR from chromatin or decrease the account activation of transcription of gadd45. Our outcomes recommend that… Continue reading Interstrand crosslinks induce DNA duplication fork holding on that in convert

Advances in flow cytometry techniques and the availability of monoclonal antibodies

Advances in flow cytometry techniques and the availability of monoclonal antibodies that detect key functional molecules on lymphocytes have contributed greatly to a more precise diagnosis of the chronic lymphoproliferative disorders. splenic lymphoma with villous lymphocytes are cyclin D1 positive.23 This study showed a good correlation between cyclin D1 expression and RT-PCR for cyclins D1… Continue reading Advances in flow cytometry techniques and the availability of monoclonal antibodies