In response to IFN-γ the latent cytoplasmic protein sign transducers and Rabbit polyclonal to AGBL2. activators of transcription 1 (Stat1) becomes phosphorylated on Y701 dimerizes and accumulates in the nucleus to activate transcription of IFN-γ-reactive genes. legislation of phosphorylation. After ligand binding to cell surface area cytokine receptors the latent cytosolic STAT protein are phosphorylated… Continue reading In response to IFN-γ the latent cytoplasmic protein sign transducers and