The ribosomal stress (RS)-p53 pathway is triggered by any stressor or genetic alteration that disrupts ribosomal biogenesis, and mediated by several ribosomal proteins (RPs), such as for example RPL11 and RPL5, which inhibit MDM2 and activate p53. malignancy cell development by dually focusing on SIRT1 and IMPDH2. DOI: http://dx.doi.org/10.7554/eLife.03077.001 strong class=”kwd-title” Study organism: human eLife… Continue reading The ribosomal stress (RS)-p53 pathway is triggered by any stressor or