Background Neuroblastoma (NB) is the most common extracranial solid tumor in children. Changes in tumorigenicity were assayed by soft agar colony forming ability. N-myc binding to miR-375 promoter was assayed by chromatin-immunoprecipitation. Results Unsupervised hierarchical clustering of miRNA microarray data segregated neuroblastic and non-neuronal cell lines and showed that specific miRNAs define each phenotype. qRT-PCR… Continue reading Background Neuroblastoma (NB) is the most common extracranial solid tumor in