We’ve investigated the mutagenicity induced in the locus in Chinese hamster ovary (CHO) cells treated with increasing concentrations of Me-lex, a minor groove selective methylating agent that efficiently generates more than 90-95% of 3-MeA DNA adducts. result in recombination and genomic deletions, therefore representing a severe threat for genome integrity. and in mammalian cells, and… Continue reading We’ve investigated the mutagenicity induced in the locus in Chinese hamster