The first organocatalytic cross aldol reaction of ketones and diethyl formylphosphonate hydrate continues to be realized through the use of easily available L-prolinamide as the catalyst. supplementary α-hydroxyphosphonates seem even more significant as all chiral organic amino acids are secondary amines. The optically enriched forms of secondary α-hydroxyphosphonates are mainly obtained through enzymatic methods 6… Continue reading The first organocatalytic cross aldol reaction of ketones and diethyl formylphosphonate