The transcription factor cAMP response element-binding protein (CREB) promotes target DNA transcription in response to cellular stimulation in brain neurons. (PKA) inhibitor H89 at a dosage that completely clogged the PKA activator (8-br-cAMP)-induced CREB phosphorylation Rabbit polyclonal to KCTD1 partly clogged the PMA-stimulated CREB phosphorylation. Furthermore, blockade of NMDA and AMPA glutamate receptors and L-type… Continue reading The transcription factor cAMP response element-binding protein (CREB) promotes target DNA