Supplementary Materialsijms-19-02470-s001. Ability and FGF1 to hinder FGF1-induced signaling cascades activation. Within the next stage the scFvs had been cloned to scFv-Fc structure, as dimeric Fc fusions confirm beneficial in potential therapeutic application. Needlessly to say, scFvs-Fc exhibited improved affinity towards FGF1 significantly. We observed solid antiproliferative activity of the scFvs and scFvs-Fc in the… Continue reading Supplementary Materialsijms-19-02470-s001. Ability and FGF1 to hinder FGF1-induced signaling cascades activation.