Tryptanthrin inhibits 5-LO item formation in intact neutrophils Previous studies showed that tryptanthrin suppresses LTB4 synthesis in neutrophils stimulated with the unphysiological stimulus A23187 ionophore (Danz et al. inflammation sites. Tryptanthrin effectively suppressed 5-LO product formation in LPS and fMLP-stimulated neutrophils with an 115256-11-6 manufacture IC50 = 0.6 ± 0.2 μM and was essentially equipotent… Continue reading Tryptanthrin inhibits 5-LO item formation in intact neutrophils Previous studies
Tag: Rabbit polyclonal to PFKFB3.
WRN the protein defective in Werner Syndrome (WS) is a multifunctional
WRN the protein defective in Werner Syndrome (WS) is a multifunctional nuclease involved in DNA damage restoration replication and genome stability maintenance. DNA double-stranded breaks to stabilize Rad51 and to limit the nuclease activity of its C-terminal binding partner MRE11. Therefore the previously unrecognized non-enzymatic function of WRN in the stabilization of nascent DNA strands… Continue reading WRN the protein defective in Werner Syndrome (WS) is a multifunctional