Ku-dependent C-NHEJ (traditional nonhomologous end joining) may be the principal DNA EJing (end joining) fix pathway in mammals. important activity. Individual Ku:LIGIII and Ku:LIGIV (DNA ligase IV) dual knockout cell lines nevertheless confirmed that LIGIII is necessary for the improved A-NHEJ activity that’s seen in Ku-deficient cells. Many nevertheless the most EJing events continued to… Continue reading Ku-dependent C-NHEJ (traditional nonhomologous end joining) may be the principal DNA