Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. memory gut motility and gastric acid secretion sleep/wake rhythm reward seeking behavior taste sensation and glucose metabolism. gene codes for the full-length G-protein coupled seven transmembrane protein GHSR1a but a truncated isoform (GHSR1b) which has… Continue reading Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as