The melanocortin 1 receptor (MC1R), a GS-coupled receptor that signals through cAMP and PKA, regulates pigmentation, adaptive tanning, and melanoma resistance. useful biomarker for the DNA repair-deficient MC1R phenotype. utilizing a 14-mer peptide matching to residues 428C441 of ATR which has the S435 residue in the framework of its indigenous PKA reputation site and that’s… Continue reading The melanocortin 1 receptor (MC1R), a GS-coupled receptor that signals through