Objectives Lung deflation and inflation during cardiac surgery with cardiopulmonary bypass plays a part in pulmonary dysfunction postoperatively. lungs. p38-MAPK and Akt Vorapaxar (SCH 530348) supplier phosphorylation improved (three to fivefold) during deflation and reinflation, and ERK1/2 phosphorylation improved (around twofold) during reinflation. SB203580 got no influence on lung physiology or ERK1/2 and Akt activation.… Continue reading Objectives Lung deflation and inflation during cardiac surgery with cardiopulmonary bypass