The identity of cells that mediate positive selection of CD8+ T cells was investigated in two T cell receptor (TCR) transgenic systems. (male antigen)CTCR+ CD8+ Capital t cells was observed in class I+ into class I-deficient chimeras. These data suggest that successful positive selection directed by hematopoietic cells depends on specific properties of the TCR… Continue reading The identity of cells that mediate positive selection of CD8+ T