Decreased expression of microRNA122 (miR122) a liver-specific microRNA is definitely regular in hepatocellular carcinoma (HCC). HCC cells reversed these results and rendered the cells even more delicate to sorafenib. Utilizing a reporter knock-in build chemical compounds had been screened and Wee1 kinase inhibitor was defined as upregulators of miR122 transcription which improved the sensitivity from… Continue reading Decreased expression of microRNA122 (miR122) a liver-specific microRNA is definitely regular