Like Bcl-2 Mcl-1 can be an essential success element for most malignancies its manifestation adding to disease and chemoresistance relapse. inactivation of Mcl-1 will not often need its elimination. Rather it can be efficiently antagonized by a BH3-like ligand tightly engaging its binding groove which is confirmed here with a structural study. Our data have… Continue reading Like Bcl-2 Mcl-1 can be an essential success element for most