The progesterone receptor (PR), a ligand-activated transcription factor, recruits the principal coactivator steroid receptor coactivator-1 (SRC-1) gene promoters. importance as the two non-degradable mutants that still interacted with PR as shown by coimmunoprecipitation didn’t stimulate transcription of exogenous and endogenous focus on genes, recommending that concomitant PR/SRC-1 ligand-dependent degradation is definitely a necessary stage for… Continue reading The progesterone receptor (PR), a ligand-activated transcription factor, recruits the principal