Proopiomelanocortin (POMC)-expressing neurons in the hypothalamus integrate a variety of central and peripheral metabolic inputs and regulate energy homeostasis by controlling energy expenditure and food intake. target for the treatment of metabolic disorders such as obesity and diabetes attempts have been made to generate potent brain-penetrant PRCP inhibitors. Here we discuss the part of PRCP… Continue reading Proopiomelanocortin (POMC)-expressing neurons in the hypothalamus integrate a variety of central